Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.48 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | CBX7 | O95931 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338243 | 0.94 | PRMT1 (0.66) | CASP6CTDSP1PRMT1SIRT1TIMP3 | |
| SCHEMBL10907966 | 0.94 | CASP6 (0.56) | CASP6CTDSP1PRMT1SIRT1TIMP3 | |
| SCHEMBL11342265 | 0.93 | TIMP3 (0.48) | CASP6CTDSP1PRMT1SIRT1TIMP3 | |
| SCHEMBL10908181 | 0.87 | CASP6 (0.48) | CASP6CTDSP1PRMT1SIRT1TIMP3 | |
| SCHEMBL10907672 | 0.87 | CASP6 (0.65) | CASP6CTDSP1PRMT1SIRT1TIMP3 | |
| SCHEMBL11339168 | 0.86 | NT5E (0.58) | CASP6CTDSP1PRMT1SIRT1TIMP3 | |
| SCHEMBL11433774 | 0.86 | CASP6 (0.64) | CASP6CTDSP1PRMT1SIRT1TIMP3 | |
| SCHEMBL11354729 | 0.85 | PRMT1 (0.44) | CASP6CTDSP1PRMT1SIRT1TIMP3 | |
| SCHEMBL11344738 | 0.84 | PRMT1 (0.71) | CASP6CTDSP1PRMT1SIRT1TIMP3 | |
| SCHEMBL11339735 | 0.84 | PRMT1 (0.44) | CASP6CTDSP1PRMT1SIRT1TIMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297372-A | ANTIARTHRITIC AGENTS; COLLAGENASE AND PROTEOLYTIC ENZYME INHIBITORS; BONE, SKIN, AND ORAL DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0013784-A1 | C-Substituted naphthalenemonosulfonic ureides, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1980-08-06 | — | — | EP | disclosed |
| US-4216164-A | Ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |