SCHEMBL113453

SCHEMBL113453

[C]1C=Cc2ccccc2O1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6889575 1.00 KDM4E (0.35) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL40747 0.68 KDM4E (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL5672949 0.68 KDM4E (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL2692229 0.67 HTR2C (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL207082 0.67 TRPA1 (0.35) KDM4EMEN1ALDH1A1MAPTKMT2A
Dibenzo[B,F]Oxepine SCHEMBL1650179 0.66 MEN1 (0.64) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL451436 0.62 ABCG2 (0.35) TRPA1
SCHEMBL20500 0.60 TRPA1 (0.42) TRPA1
SCHEMBL7098395 0.60 MAPT (0.38) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL2493361 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960345-A Polycarbonate resin, method for producing same, and optical lens 三菱瓦斯化学株式会社 2023-04-14 CN claimed
CN-114752053-A Polycarbonate resin, method for producing same, and optical lens 三菱瓦斯化学株式会社 2022-07-15 CN claimed
CN-114716658-A Polycarbonate resin, method for producing same, and optical lens 三菱瓦斯化学株式会社 2022-07-08 CN claimed
CN-113518934-A Thermoplastic resin, method for producing same, and optical lens 三菱瓦斯化学株式会社 2021-10-19 CN claimed
CN-113348168-A Heterocyclic derivatives 默克专利有限公司 2021-09-03 CN claimed
CN-111094223-A Binaphthyl compounds 罗伊特化学仪器制造公司 2020-05-01 CN claimed
CN-111094389-A Polycarbonate resin, method for producing same, and optical lens 三菱瓦斯化学株式会社 2020-05-01 CN claimed
EP-1581476-B1 AMIDES AS 11-BETA HYDROXYSTEROID DEHYDROGENASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2016-11-16 EP claimed
CN-103261336-A Surface modified organic black pigments, surface modified carbon blacks, pigment mixtures using them, and low dielectric black dispersions, coatings, films, black matrices, and devices containing same CABOT CORP 2013-08-21 CN claimed
EP-2542528-A1 HETEROCYCLIC AMIDES AS ROCK INHIBITORS Amakem NV (BE) 2013-01-09 EP claimed
CN-1300288-A Water soluble azoles as broad-spectrum antifungals JANSSEN PHARMACEUTICA NV (BE) 2001-06-20 CN claimed
CN-1286255-A Pyridine compounds, their preparation method and pharmaceutical compositions contg them ADIR (FR) 2001-03-07 CN claimed
CN-1275123-A Prostaglandin agonists and their use to treat bone disorders PFIZER (US) 2000-11-29 CN claimed
EP-0182594-B1 OPTICAL RECORDING ELEMENTS COMPRISING TELLUROPYRYLIUM DYES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-10-25 EP claimed
US-4855213-A SPECTRA SENSITIZERS EASTMAN KODAK COMPANY (US) 1989-08-08 US claimed
EP-0068877-B1 TELLUROPYRYLIUM COMPOUNDS AND ELECTRON DONATING PHOTOCONDUCTIVE COMPOSITIONS CONTAINING SAME EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-07-29 EP claimed
EP-0182594-A1 Optical recording elements comprising telluropyrylium dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-05-28 EP claimed
US-4584258-A INFRARED ABSORBING DYE-CONTAINING COATING FOR OPTICAL RECORDING MEDIA EASTMAN KODAK COMPANY (US) 1986-04-22 US claimed
EP-0068877-A2 Telluropyrylium compounds and electron donating photoconductive compositions containing same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-01-05 EP claimed
US-4365017-A ELECTROGRAPHY EASTMAN KODAK COMPANY (US) 1982-12-21 US claimed