Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113453 | 1.00 | KDM4E (0.35) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL40747 | 0.68 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5672949 | 0.68 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2692229 | 0.67 | HTR2C (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL207082 | 0.67 | TRPA1 (0.35) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| Dibenzo[B,F]Oxepine SCHEMBL1650179 | 0.66 | MEN1 (0.64) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL451436 | 0.62 | ABCG2 (0.35) | TRPA1 | |
| SCHEMBL20500 | 0.60 | TRPA1 (0.42) | TRPA1 | |
| SCHEMBL7098395 | 0.60 | MAPT (0.38) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2493361 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428858-B1 | Hydrophilic marker dyes based on benzopyrylo-polymethines | DYOMICS GMBH (DE) | 2013-01-30 | — | — | EP | disclosed |
| EP-1428858-A1 | Hydrophilic marker dyes based on benzopyrylo-polymethines | Dyomics GmbH (DE) | 2004-06-16 | — | — | EP | disclosed |