SCHEMBL2493361

SCHEMBL2493361

[CH]1Oc2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5841466 0.78 DRD2 (0.37)
SCHEMBL630372 0.76 LMNA (0.31)
SCHEMBL6680055 0.73 ALDH1A1 (0.41)
Benzofuran SCHEMBL20184214 0.71
SCHEMBL3556 0.71
SCHEMBL3557 0.69
SCHEMBL29142226 0.69 KDM4E (0.34)
SCHEMBL315326 0.68 KDM4E (0.33)
SCHEMBL16179 0.67 KDM4E (0.36)
SCHEMBL276861 0.67 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9080046-B2 Epoxybenzyl-terminated poly(arylene ether)s, method for preparation thereof, and curable compositions comprising same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-07-14 US claimed
US-20140058014-A1 EPOXYBENZYL-TERMINATED POLY(ARYLENE ETHER)S, METHOD FOR PREPARATION THEREOF, AND CURABLE COMPOSITIONS COMPRISING SAME SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-02-27 US claimed
US-8598281-B2 Epoxybenzyl-terminated poly(arylene ether)s, method for preparation thereof, and curable compositions comprising same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-12-03 US claimed
EP-2576561-A1 HETEROCYCLIC COMPOUNDS AS JANUS KINASE INHIBITORS Biocryst Pharmaceuticals, Inc. (US) 2013-04-10 EP claimed
WO-2013032739-A2 EPOXYBENZYL-TERMINATED POLY(ARYLENE ETHER)S, METHOD FOR PREPARATION THEREOF, AND CURABLE COMPOSITIONS COMPRISING SAME SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-03-07 WO claimed
US-20130059127-A1 EPOXYBENZYL-TERMINATED POLY(ARYLENE ETHER)S, METHOD FOR PREPARATION THEREOF, AND CURABLE COMPOSITIONS COMPRISING SAME SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2013-03-07 US claimed
WO-2011150356-A1 HETEROCYCLIC COMPOUNDS AS JANUS KINASE INHIBITORS BIOCRYST PHARMACEUTICALS, INC. (US) 2011-12-01 WO claimed
EP-1951725-B1 N-SULFAMOYL-N -BENZOPYRANPIPERIDINES AS INHBITORS OF CARBONIC ANHYDRASES ABBOTT PRODUCTS GMBH (DE) 2010-11-03 EP claimed
US-7547708-B2 N-sulfamoyl-N′-benzopyranpiperidine compounds and uses thereof SOLVAY PHARMACEUTICALS, INC. (DE) 2009-06-16 US claimed
US-20070117823-A1 N-sulfamoyl-N'-benzopyranpiperidine compounds and uses thereof SOLVAY PHARMACEUTICALSS GMBH (DE) 2007-05-24 US claimed
WO-2001051095-A2 PARAMAGNETIC DOTA DERIVATIVES, PHARMACEUTICAL AGENTS CONTAINING THE SAME, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE FOR THE MR IMAGING OF NECROSIS AND INFARCTION SCHERING AKTIENGESELLSCHAFT (DE) 2001-07-19 WO claimed
EP-2158264-B1 BLENDS OF FLUOROALKYL-CONTAINING ESTER OLIGOMERS WITH POLYDICARBODIIMIDE(S) 3M INNOVATIVE PROPERTIES CO (US) 2019-04-10 EP disclosed
US-9828722-B2 Blends of fluoroalkyl-containing ester oligomers with polycarbodiimide(s) 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-11-28 US disclosed
US-9080046-B2 Epoxybenzyl-terminated poly(arylene ether)s, method for preparation thereof, and curable compositions comprising same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-07-14 US disclosed
US-9080046-B2 Epoxybenzyl-terminated poly(arylene ether)s, method for preparation thereof, and curable compositions comprising same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-07-14 US disclosed
WO-2002072657-A1 WATER- AND OIL-REPELLENCY IMPARTING URETHANE OLIGOMERS COMPRISING PERFLUOROALKYL MOIETIES 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-09-19 WO disclosed
WO-2002014443-A2 URETHANE-BASED STAIN-RELEASE COATINGS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-02-21 WO disclosed
WO-2001051095-A2 PARAMAGNETIC DOTA DERIVATIVES, PHARMACEUTICAL AGENTS CONTAINING THE SAME, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE FOR THE MR IMAGING OF NECROSIS AND INFARCTION SCHERING AKTIENGESELLSCHAFT (DE) 2001-07-19 WO disclosed
US-6059000-A Apparatus for manufacturing bead filter SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2000-05-09 US disclosed
US-5851341-A Method for manufacturing bead filter using an epoxy resin gel SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 1998-12-22 US disclosed