Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484328 | 0.78 | NPC1 (0.55) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| Drometrizole SCHEMBL29350665 | 0.78 | NPC1 (1.00) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| Drometrizole SCHEMBL27755727 | 0.78 | NPC1 (1.00) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| Drometrizole SCHEMBL2548258 | 0.78 | NPC1 (1.00) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| Drometrizole SCHEMBL15616 | 0.78 | NPC1 (1.00) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| Drometrizole SCHEMBL7796640 | 0.77 | NPC1 (0.90) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL50784 | 0.75 | LMNA (0.56) | NPC1RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL29422754 | 0.75 | NPC1 (0.75) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL906023 | 0.75 | NPC1 (0.75) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL11878851 | 0.75 | LMNA (0.46) | LMNAALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031302-A2 | Benzotriazole UV absorbers, process for their preparation and stabilized mixtures | CIBA-GEIGY AG (CH) | 1981-07-01 | — | — | EP | disclosed |