Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.32 |
| ▸ | GRM5 | P41594 | 4/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.32 |
| ▸ | GRM6 | O15303 | 2/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14118138 | 0.85 | POLB (0.39) | POLBTDP1HSD11B1GRM2GRM5 | |
| SCHEMBL7741675 | 0.83 | POLB (0.38) | POLBTDP1HSD11B1GRM2GRM5 | |
| SCHEMBL14243718 | 0.81 | HSD11B1 (0.40) | GABRR1POLBTDP1HSD11B1GRM2 | |
| SCHEMBL7258876 | 0.78 | CYP2C9 (0.42) | POLBTDP1HSD11B1GRM2GRM3 | |
| SCHEMBL14026146 | 0.73 | CYP2C9 (0.30) | — | |
| SCHEMBL19859959 | 0.73 | HSD11B1 (0.48) | POLBTDP1HSD11B1GRM2GRM5 | |
| SCHEMBL160953 | 0.73 | HSD11B1 (0.48) | POLBTDP1HSD11B1GRM2GRM5 | |
| SCHEMBL16698251 | 0.73 | HSD11B1 (0.48) | POLBTDP1HSD11B1GRM2GRM5 | |
| Hydrochloric Acid SCHEMBL3051989 | 0.71 | HSD11B1 (0.46) | POLBTDP1HSD11B1GRM2GRM5 | |
| SCHEMBL31349739 | 0.71 | HSD11B1 (0.46) | POLBTDP1HSD11B1GRM2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273704-A | N-Adamantane-substituted tetrapeptide amides | G. D. SEARLE & CO. (US) | 1981-06-16 | — | — | US | disclosed |