Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438009 | 0.73 | ESR1 (0.34) | ESR1ESR2MAOAMAOBALDH1A1 | |
| SCHEMBL9900562 | 0.73 | ESR1 (0.34) | ESR1ESR2MAOAMAOBALDH1A1 | |
| SCHEMBL11358607 | 0.72 | DRD2 (0.49) | ESR1ESR2MAOAMAOBDRD2 | |
| SCHEMBL4860941 | 0.72 | MAOB (0.38) | ESR1ESR2MAOAMAOBDRD2 | |
| SCHEMBL16200796 | 0.72 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL13805578 | 0.70 | MAP3K14 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9904289 | 0.69 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL13805576 | 0.69 | MAP3K14 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9904807 | 0.68 | MAOA (0.33) | ESR1ESR2MAOAMAOBALDH1A1 | |
| SCHEMBL18199054 | 0.67 | HPGD (0.33) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004366-B1 | HAIR DYEING COMPOSITIONS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-07-08 | — | — | EP | disclosed |
| EP-0004366-A2 | Hair dyeing compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1979-10-03 | — | — | EP | disclosed |