SCHEMBL11345689

SCHEMBL11345689

CCCCCCC=C[Si](Cl)(Cl)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SOAT2 O75908 1/20 0.42
SOAT1 P35610 1/20 0.42
FAAH O00519 5/20 0.40
EPHX2 P34913 4/20 0.40
CES1 P23141 2/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
MMP2 P08253 2/20 0.37
F7 P08709 2/20 0.37
F3 P13726 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
ECE1 P42892 1/20 0.37
SGMS1 Q86VZ5 1/20 0.37
SGMS2 Q8NHU3 1/20 0.37
MUS81 Q96NY9 1/20 0.37
HSD17B10 Q99714 1/20 0.37
SAE1 Q9UBE0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21383346 0.93 CYP1A2 (0.35) SOAT2SOAT1FAAHEPHX2CES1
SCHEMBL21383347 0.93 CYP1A2 (0.35) SOAT2SOAT1FAAHEPHX2CES1
SCHEMBL16210117 0.79 FAAH (0.43) SOAT2SOAT1FAAHEPHX2CES1
SCHEMBL16209833 0.79 FAAH (0.43) SOAT2SOAT1FAAHEPHX2CES1
SCHEMBL16210115 0.79 FAAH (0.43) SOAT2SOAT1FAAHEPHX2CES1
SCHEMBL16209982 0.79 FAAH (0.43) SOAT2SOAT1FAAHEPHX2CES1
SCHEMBL21383018 0.77 CYP1A2 (0.34) SOAT2SOAT1FAAHEPHX2CES1
SCHEMBL21383020 0.77 CYP1A2 (0.34) SOAT2SOAT1FAAHEPHX2CES1
SCHEMBL9219897 0.74 MGAM (0.39) SOAT2SOAT1FAAHEPHX2CES1
SCHEMBL9219901 0.74 MGAM (0.39) SOAT2SOAT1FAAHEPHX2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4268682-A ω-Alkenyl silanes and αω-silyl alkanes EXXON RESEARCH & ENGINEERING CO. (US) 1981-05-19 US disclosed