Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 5/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | BID | P55957 | 3/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21383346 | 1.00 | CYP1A2 (0.35) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11345689 | 0.93 | SOAT2 (0.42) | SOAT2SOAT1FAAHEPHX2CES1 | |
| SCHEMBL21383020 | 0.83 | CYP1A2 (0.34) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21383018 | 0.83 | CYP1A2 (0.34) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9219897 | 0.80 | MGAM (0.39) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9219901 | 0.80 | MGAM (0.39) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21383437 | 0.79 | CYP1A2 (0.35) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21383438 | 0.79 | CYP1A2 (0.35) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21383293 | 0.79 | CYP1A2 (0.35) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21383263 | 0.77 | EPHX2 (0.38) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768732-A1 | PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY | Dow Global Technologies LLC (US) | 2021-01-27 | — | — | EP | disclosed |
| EP-3768733-A1 | SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME | Dow Global Technologies LLC (US) | 2021-01-27 | — | — | EP | disclosed |
| US-20210017311-A1 | SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME | DOW GLOBAL TECHNOLOGIES LLC | 2021-01-21 | — | — | US | disclosed |
| US-20210017195-A1 | PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-01-21 | — | — | US | disclosed |
| CN-111868110-A | Silicon-terminated telechelic polyolefin compositions and methods of making the same | 陶氏环球技术有限责任公司 | 2020-10-30 | — | — | CN | disclosed |
| WO-2019182992-A1 | PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019182993-A1 | SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210017195-A1 | PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY | ZRANB2, NISCH, ZKSCAN2 | CYP1A2 3051/4885TSHR 3950/4885CYP3A4 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.