Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274150 | 0.92 | CYP2D6 (0.46) | CYP3A4CYP2D6TSHRSIGMAR1ALDH1A1 | |
| SCHEMBL11279763 | 0.88 | CYP3A4 (0.45) | CYP3A4HSD17B10OPRM1CYP2D6TSHR | |
| SCHEMBL11283216 | 0.80 | CYP2D6 (0.49) | CYP3A4CYP2D6TSHRALDH1A1POLB | |
| SCHEMBL11277475 | 0.79 | CYP3A4 (0.51) | CYP3A4HSD17B10OPRM1CYP2D6TSHR | |
| SCHEMBL9337560 | 0.70 | MAPK1 (0.55) | MAPK1OPRM1SIGMAR1ALDH1A1 | |
| SCHEMBL20571573 | 0.70 | CYP3A4 (0.59) | CYP3A4HSD17B10OPRM1CYP2D6TSHR | |
| SCHEMBL11278642 | 0.70 | SLC6A3 (0.51) | OPRM1SIGMAR1 | |
| SCHEMBL2262610 | 0.69 | CYP3A4 (0.56) | CYP3A4HSD17B10CYP2D6TSHROPRL1 | |
| SCHEMBL4817148 | 0.69 | CYP3A4 (0.56) | CYP3A4HSD17B10CYP2D6TSHROPRL1 | |
| SCHEMBL6132006 | 0.68 | CYP2D6 (0.46) | CYP3A4HSD17B10CYP2D6TSHROPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056699-A1 | Organic peroxides and use of same | AUSIMONT S.p.A. (IT) | 1982-07-28 | — | — | EP | claimed |
| EP-0056699-A1 | Organic peroxides and use of same | AUSIMONT S.p.A. (IT) | 1982-07-28 | — | — | EP | disclosed |