Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279763 | 0.91 | CYP3A4 (0.45) | CYP3A4HSD17B10SIGMAR1OPRL1POLB | |
| SCHEMBL11278642 | 0.87 | SLC6A3 (0.51) | SIGMAR1OPRM1ACHE | |
| SCHEMBL11283216 | 0.83 | CYP2D6 (0.49) | CYP3A4POLBALDH1A1TSHRCYP2D6 | |
| SCHEMBL11345707 | 0.79 | CYP3A4 (0.42) | CYP3A4HSD17B10SIGMAR1OPRL1POLB | |
| SCHEMBL20571573 | 0.79 | CYP3A4 (0.59) | CYP3A4HSD17B10SIGMAR1OPRL1POLB | |
| SCHEMBL2147364 | 0.76 | CYP3A4 (0.56) | CYP3A4HSD17B10SIGMAR1OPRL1POLB | |
| SCHEMBL12013906 | 0.73 | SIGMAR1 (0.65) | CYP3A4HSD17B10SIGMAR1OPRL1POLB | |
| SCHEMBL2629504 | 0.72 | ALDH1A1 (0.62) | CYP3A4HSD17B10SIGMAR1OPRL1POLB | |
| SCHEMBL16973869 | 0.72 | OPRL1 (0.59) | CYP3A4HSD17B10SIGMAR1OPRL1POLB | |
| Ammonia Solution, Strong SCHEMBL14735243 | 0.72 | SIGMAR1 (0.63) | CYP3A4HSD17B10SIGMAR1OPRL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056699-A1 | Organic peroxides and use of same | AUSIMONT S.p.A. (IT) | 1982-07-28 | — | — | EP | claimed |
| EP-0056699-A1 | Organic peroxides and use of same | AUSIMONT S.p.A. (IT) | 1982-07-28 | — | — | EP | disclosed |