Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11353969 | 0.79 | PTPN1 (0.42) | PTPN1PTPN11ALOX15ALOX12MEN1 | |
| SCHEMBL11350786 | 0.79 | PTPN1 (0.38) | PTPN1PTPN11ALOX15ALOX12MEN1 | |
| SCHEMBL11408208 | 0.76 | ALDH1A1 (0.37) | KMT2APOLB | |
| SCHEMBL11352012 | 0.75 | NQO1 (0.37) | MEN1KMT2ACYP3A4ESR2 | |
| SCHEMBL11347995 | 0.74 | CYP3A4 (0.41) | ALOX15MEN1KMT2ACYP3A4CA5A | |
| SCHEMBL11345628 | 0.71 | GABRA1 (0.41) | ALOX15ALOX12CYP3A4GABRA1GABRB2 | |
| SCHEMBL204196 | 0.70 | GABRA1 (0.50) | PTPN1PTPN11ALOX15ALOX12MEN1 | |
| SCHEMBL10477405 | 0.70 | PTPN1 (0.39) | PTPN1PTPN11ALOX15ALOX12MEN1 | |
| SCHEMBL27060230 | 0.69 | CYP3A4 (0.39) | PTPN1PTPN11ALOX15ALOX12CYP3A4 | |
| SCHEMBL69820 | 0.69 | GABRA1 (0.55) | PTPN1PTPN11ALOX15ALOX12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001910-B1 | PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF | MONSANTO COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| EP-0001909-B1 | PREPARATION OF 1,2-BIS(4-HYDROXYARYL)ETHANES BY ONE-STEP DEHYDROHALOGENATION-REARRANGEMENT-HYDROGENATION OF 1,1-BIS(4-HYDROXYARYL)-2-HALOETHANES, WHICH MAY BE FOLLOWED BY ACYLATION | MONSANTO COMPANY (US) | 1981-08-12 | — | — | EP | disclosed |
| US-4189610-A | Preparation of 4,4-dioxy-substituted stilbenes | MONSANTO COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4156787-A | HYDROGENATION CATALYST | MONSANTO COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| EP-0001910-A1 | Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |
| EP-0001909-A1 | Preparation of 1,2-bis(4-hydroxyaryl)ethanes by one-step dehydrohalogenation-rearrangement-hydrogenation of 1,1-bis(4-hydroxyaryl)-2-haloethanes, which may be followed by acylation | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |