Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408208 | 0.83 | ALDH1A1 (0.37) | MAPTHSD17B10ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11351915 | 0.81 | NQO1 (0.37) | NQO1PTGS2AKR1C3AKR1C2LTA4H | |
| SCHEMBL11349748 | 0.81 | NQO1 (0.37) | NQO1PTGS2AKR1C3AKR1C2LTA4H | |
| SCHEMBL11365534 | 0.79 | NQO1 (0.38) | NQO1PTGS2AKR1C3AKR1C2LTA4H | |
| SCHEMBL11345871 | 0.75 | PTPN1 (0.38) | ESR2CYP3A4MEN1KMT2A | |
| SCHEMBL11353888 | 0.70 | THRB (0.34) | PTGS2AKR1C3AKR1C2MAPTTSHR | |
| SCHEMBL25329709 | 0.70 | GABRA1 (0.44) | NQO1PTGS2LTA4HMAPTHSD17B10 | |
| SCHEMBL28919511 | 0.70 | TSHR (0.46) | NQO1MAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL11365947 | 0.69 | L3MBTL1 (0.36) | MAPTHSD17B10TSHRALDH1A1HPGD | |
| SCHEMBL1683212 | 0.67 | NQO1 (0.65) | NQO1PTGS2LTA4HMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001910-B1 | PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF | MONSANTO COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4189610-A | Preparation of 4,4-dioxy-substituted stilbenes | MONSANTO COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0001910-A1 | Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |