SCHEMBL11345997

SCHEMBL11345997

[CH2]CCC(O)CC(O)CO

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.43
CYP3A4 P08684 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 2/20 0.42
ALDH1A1 P00352 1/20 0.42
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL270137 0.85
SCHEMBL28271539 0.82
SCHEMBL4961158 0.80 THRB (0.50) LMNAALDH1A1THRB
SCHEMBL22268 0.78
SCHEMBL9333183 0.78
SCHEMBL5519959 0.78
SCHEMBL4557350 0.78
SCHEMBL1657231 0.78
SCHEMBL14686485 0.77 LMNA (0.36) USP2CYP3A4SMN1; SMN2LMNAALDH1A1
SCHEMBL2914655 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0035363-A1 Indane derivatives, methods of their preparation and compositions containing them KEFALAS A/S (DK) 1981-09-09 EP disclosed