⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28271539 | 0.97 | — | — | |
| SCHEMBL4961158 | 0.94 | THRB (0.50) | — | |
| SCHEMBL11345997 | 0.85 | USP2 (0.43) | — | |
| SCHEMBL2045200 | 0.82 | — | — | |
| SCHEMBL270579 | 0.81 | — | — | |
| SCHEMBL7849858 | 0.79 | — | — | |
| SCHEMBL7157355 | 0.78 | THRB (0.71) | — | |
| SCHEMBL10581335 | 0.78 | THRB (0.71) | — | |
| SCHEMBL2207927 | 0.78 | THRB (0.71) | — | |
| SCHEMBL9742446 | 0.78 | THRB (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450283-B | 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2024-05-07 | — | — | CN | claimed |
| EP-4003988-A1 | 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | Les Laboratoires Servier (FR) | 2022-06-01 | — | — | EP | claimed |
| CN-114450283-A | 3, 6-diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2022-05-06 | — | — | CN | claimed |
| WO-2021018857-A1 | 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | LES LABORATOIRES SERVIER (FR) | 2021-02-04 | — | — | WO | claimed |
| CN-103275311-B | Polylactide-loaded prodrug and preparation method thereof | UNIV XIANGTAN | 2015-02-25 | — | — | CN | claimed |
| CN-103275312-B | Polylactide containing side hydroxy or side carboxy functional group and preparation method thereof | UNIV XIANGTAN | 2015-01-21 | — | — | CN | claimed |
| CN-103275311-A | Polylactide-loaded prodrug and preparation method thereof | UNIV XIANGTAN | 2013-09-04 | — | — | CN | claimed |
| CN-103275312-A | Polylactide containing side hydroxy or side carboxy functional group and preparation method thereof | UNIV XIANGTAN | 2013-09-04 | — | — | CN | claimed |
| US-20070015792-A1 | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | MSD K.K. (JP) | 2007-01-18 | — | — | US | claimed |
| CN-114450283-B | 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2024-05-07 | — | — | CN | disclosed |
| CN-110740991-B | Novel biphenyl compound or salt thereof | 大鹏药品工业株式会社 | 2023-07-04 | — | — | CN | disclosed |
| EP-3632443-B1 | ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-06-07 | — | — | EP | disclosed |
| EP-3381896-B1 | BIPHENYL COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-01-18 | — | — | EP | disclosed |
| US-20220390458-A1 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-12-08 | — | — | US | disclosed |
| EP-0061425-A2 | Thiazole derivatives, processes for their preparation, medicaments containing them and their use | CIBA-GEIGY AG (CH) | 1982-09-29 | — | — | EP | disclosed |
| EP-0019843-B1 | SISOMICIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
| US-4312859-A | ANTIBIOTICS, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| EP-0019843-A1 | Sisomicin derivatives, process for their preparation and their use as medicines | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |
| US-4235888-A | SISOMYCIN-TYPE ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |
| EP-0007996-A1 | 4,6-Di-0-(Aminoglycosyl)-1,3-diaminocyclitols, process for their preparation and pharmaceutical compositions containing them | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |