⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275147 | 0.81 | NOS1 (0.42) | — | |
| SCHEMBL30102029 | 0.79 | HTR3E (0.58) | — | |
| SCHEMBL7870699 | 0.79 | HTR3E (0.58) | — | |
| SCHEMBL7870702 | 0.79 | HTR3E (0.58) | — | |
| SCHEMBL3181009 | 0.79 | HTR3E (0.58) | — | |
| SCHEMBL8632771 | 0.75 | — | — | |
| SCHEMBL1374335 | 0.75 | — | — | |
| SCHEMBL12056079 | 0.75 | — | — | |
| SCHEMBL5527357 | 0.75 | HTR3E (0.48) | — | |
| SCHEMBL8631096 | 0.75 | HTR3E (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129740-A | Process for the preparation of para-nitroso-diphenylhydroxylamines | AKZONA INCORPORATED (US) | 1978-12-12 | — | — | US | claimed |
| CN-116120185-B | Method for preparing nitroso-containing aromatic compound from amino-containing aromatic compound | 安徽省化工研究院 | 2025-01-28 | — | — | CN | disclosed |
| CN-116120185-A | Method for preparing nitroso-containing aromatic compound from amino-containing aromatic compound | 安徽省化工研究院 | 2023-05-16 | — | — | CN | disclosed |
| CN-112774670-A | Application of rhodium monatomic catalyst in reaction for preparing m-chloroaniline through selective hydrogenation of m-chloronitrobenzene | 中国科学院大连化学物理研究所 | 2021-05-11 | — | — | CN | disclosed |
| CN-108658812-B | Alpha-alkoxy-alpha-nitrogen oxyacetate derivative and synthesis method and application thereof | 华东师范大学 | 2020-12-22 | — | — | CN | disclosed |
| US-9173869-B2 | Mediators of hedgehog signaling pathways, compositions and uses related thereto | CURIS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20140228564-A1 | PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-08-14 | — | — | US | disclosed |
| US-20140228564-A1 | PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-08-14 | — | — | US | disclosed |
| US-8680335-B2 | Processes of enantioselectively forming an aminoxy compound and an 1,2-oxazine compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-03-25 | — | — | US | disclosed |
| US-8680335-B2 | Processes of enantioselectively forming an aminoxy compound and an 1,2-oxazine compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-03-25 | — | — | US | disclosed |
| US-20110077256-A1 | MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO | GUICHERIT OIVIN M | 2011-03-31 | — | — | US | disclosed |
| US-7700597-B2 | Substituted piperazines as CB1 antagonists | SCHERING CORPORATION (US) | 2010-04-20 | — | — | US | disclosed |
| US-7700597-B2 | Substituted piperazines as CB1 antagonists | SCHERING CORPORATION (US) | 2010-04-20 | — | — | US | disclosed |
| US-20100029607-A1 | Substituted Piperazines as CB1 Antagonists | SCHERING CORPORATION | 2010-02-04 | — | — | US | disclosed |
| US-20100029607-A1 | Substituted Piperazines as CB1 Antagonists | SCHERING CORPORATION | 2010-02-04 | — | — | US | disclosed |
| EP-0009267-B1 | PROCESS FOR THE PREPARATION OF P-NITROSO-DIPHENYLHYDROXYLAMINES | AKZO N.V. (NL) | 1981-11-25 | — | — | EP | disclosed |
| US-4242523-A | Process for the preparation of para-nitroso-diphenyl-hydroxylamines | AKZONA INCORPORATED (US) | 1980-12-30 | — | — | US | disclosed |
| EP-0009267-A1 | Process for the preparation of p-nitroso-diphenylhydroxylamines | AKZO N.V. (NL) | 1980-04-02 | — | — | EP | disclosed |
| US-4129740-A | Process for the preparation of para-nitroso-diphenylhydroxylamines | AKZONA INCORPORATED (US) | 1978-12-12 | — | — | US | disclosed |
| US-3989680-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1976-11-02 | — | — | US | disclosed |