SCHEMBL1134725

SCHEMBL1134725

COc1ccc2c(c1)=c1ccc(OC)cc1=2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.56
CA2 P00918 4/20 0.56
CA7 P43166 4/20 0.56
CA9 Q16790 4/20 0.56
CA12 O43570 2/20 0.56
CA14 Q9ULX7 2/20 0.56
CYP1A2 P05177 2/20 0.50
CYP2A6 P11509 1/20 0.50
ALDH1A1 P00352 7/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 3/20 0.46
TSHR P16473 1/20 0.46
GFER P55789 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ACHE P22303 2/20 0.46
THRB P10828 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP1A1 P04798 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346791 1.00 CA1 (0.56) CA1CA2CA7CA9CA12
SCHEMBL29153309 0.92 CYP1A2 (0.56) CA1CA2CA7CA9CA12
SCHEMBL443070 0.75 CYP1A2 (0.79) CA1CA2CA7CA9CA12
SCHEMBL29447161 0.75 CYP1A2 (0.79) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL21802643 0.73 CA1 (1.00) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.73 CA1 (1.00) CA1CA2CA7CA9CA12
SCHEMBL17923610 0.73 MAPT (0.50) CYP1A2CYP2A6ALDH1A1MEN1KMT2A
SCHEMBL443528 0.71 CYP2A6 (0.80) CA1CA2CA7CA9CA12
SCHEMBL346790 0.71 ALDH1A1 (0.64) CA1CA2CA7CA9CA12
SCHEMBL6891918 0.71 CYP1A2 (0.71) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285340-B1 INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2013-07-31 EP disclosed
EP-2285340-A2 INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF 3M Innovative Properties Company (US) 2011-02-23 EP disclosed
WO-2009152211-A2 INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-17 WO disclosed
EP-2133063-A1 Initiator system with biphenylene derivates, method of production and use thereof 3M Innovative Properties Company (US) 2009-12-16 EP disclosed