SCHEMBL346790

SCHEMBL346790

COc1ccc2c(c1)-c1cc(OC)ccc1-2

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
MEN1 O00255 3/20 0.64
MAPT P10636 3/20 0.64
KMT2A Q03164 3/20 0.64
CYP1A2 P05177 3/20 0.64
CYP3A4 P08684 2/20 0.64
CYP2D6 P10635 2/20 0.64
CYP2C9 P11712 2/20 0.64
CYP2C19 P33261 2/20 0.64
HPGD P15428 1/20 0.64
RAB9A P51151 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
APP P05067 1/20 0.64
SNCA P37840 1/20 0.64
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA7 P43166 3/20 0.56
CA9 Q16790 3/20 0.56
CA12 O43570 2/20 0.56
CA14 Q9ULX7 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1134724 1.00 ALDH1A1 (0.64) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL31669020 0.92 GPR3 (0.59) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL25693544 0.92 GPR3 (0.59) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL2993382 0.86 CA1 (0.53) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL10885799 0.86 CA1 (0.53) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL23111388 0.85 CA1 (0.57) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL29595732 0.85 CA1 (0.57) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL7786812 0.85 CA1 (0.57) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL30629120 0.85 CA1 (0.57) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL28155812 0.85 CA1 (0.57) ALDH1A1MEN1MAPTKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285340-B1 INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2013-07-31 EP disclosed
EP-2285340-B1 INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2013-07-31 EP disclosed
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-8048982-B2 Method for producing aromatic compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-01 US disclosed
CN-101001900-B Process for producing aromatic compound polymer SUMITOMO CHEMICAL CO 2011-04-20 CN disclosed
EP-2285340-A2 INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF 3M Innovative Properties Company (US) 2011-02-23 EP disclosed
CN-101914111-A The preparation method of aromatic compound polymer SUMITOMO CHEMICAL CO 2010-12-15 CN disclosed
EP-2241548-A1 Vanadium di-nuclear complex Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
EP-2241547-A1 Method for producing aromatic compound polymer Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
WO-2009152211-A2 INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-17 WO disclosed
WO-2009152211-A2 INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-17 WO disclosed
EP-2133063-A1 Initiator system with biphenylene derivates, method of production and use thereof 3M Innovative Properties Company (US) 2009-12-16 EP disclosed
EP-2133063-A1 Initiator system with biphenylene derivates, method of production and use thereof 3M Innovative Properties Company (US) 2009-12-16 EP disclosed
US-20090018309-A1 Method for Producing Aromatic Compound Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
CN-101001900-A Process for producing aromatic compound polymer SUMITOMO CHEMICAL CO (JP) 2007-07-18 CN disclosed
EP-1767560-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER Sumitomo Chemical Company, Limited (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018309-A1 Method for Producing Aromatic Compound Polymer PAH, MAOA, AHR ALDH1A1 302/4885MEN1 4081/4885MAPT 2617/4885
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER PAH, MAOA, AHR ALDH1A1 292/4885MEN1 4122/4885MAPT 2638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.