Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB9 | P28065 | 4/20 | 0.39 |
| ▸ | APLNR | P35414 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | REN | P00797 | 3/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435639 | 0.85 | PSMB9 (0.44) | PSMB9APLNRF2REN | |
| SCHEMBL11435645 | 0.85 | PSMB9 (0.44) | PSMB9APLNRF2REN | |
| SCHEMBL11240079 | 0.85 | PSMB9 (0.52) | PSMB9APLNRF2REN | |
| SCHEMBL11240100 | 0.85 | PSMB9 (0.52) | PSMB9APLNRF2REN | |
| SCHEMBL11436789 | 0.76 | PSMB9 (0.43) | PSMB9APLNRF2REN | |
| SCHEMBL11436783 | 0.76 | PSMB9 (0.43) | PSMB9APLNRF2REN | |
| SCHEMBL11092435 | 0.74 | REN (0.47) | REN | |
| SCHEMBL11435651 | 0.73 | CTRB1 (0.52) | PSMB9REN | |
| SCHEMBL11435644 | 0.73 | CTRB1 (0.52) | PSMB9REN | |
| SCHEMBL6516908 | 0.73 | REN (0.58) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261884-A | DESIRABLE BIOLOGICAL PROPERTIES AND STABILITY TO ENZYME CLEAVAGE | RESEARCH CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |