Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11382005 | 1.00 | LMNA (0.33) | LMNAMAPTHTTTSHRPOLB | |
| SCHEMBL9520258 | 1.00 | LMNA (0.33) | LMNAMAPTHTTTSHRPOLB | |
| SCHEMBL11217037 | 1.00 | LMNA (0.33) | LMNAMAPTHTTTSHRPOLB | |
| SCHEMBL11503301 | 1.00 | LMNA (0.33) | LMNAMAPTHTTTSHRPOLB | |
| SCHEMBL10828081 | 0.86 | HPGD (0.34) | LMNAMAPTHTTTSHRPOLB | |
| SCHEMBL10832189 | 0.86 | HPGD (0.34) | LMNAMAPTHTTTSHRPOLB | |
| SCHEMBL10483036 | 0.86 | HPGD (0.34) | LMNAMAPTHTTTSHRPOLB | |
| SCHEMBL11173404 | 0.86 | LMNA (0.35) | LMNAMAPTHTTTSHRPOLB | |
| SCHEMBL9520759 | 0.84 | LMNA (0.43) | LMNATSHRTDP1NPSR1 | |
| SCHEMBL11292470 | 0.84 | LMNA (0.43) | LMNATSHRTDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012722-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 3-SUBSTITUTED 2-(2',2'-DIHALOVINYL)-CYCLOPROPANE-1-CARBOXYLIC ACIDS AND THEIR DERIVATIVES; 4-(2',2',2'-TRIHALOETHYL)-CYCLOBUTANE-1-SULPHONIC ACID SALTS AND THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1981-12-09 | — | — | EP | disclosed |