SCHEMBL9520258

SCHEMBL9520258

CC1(C)C(C=C(Cl)Cl)C1OC(=O)O

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
TSHR P16473 2/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
HPGD P15428 1/20 0.33
ADRA2A P08913 1/20 0.32
CNR1 P21554 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11382005 1.00 LMNA (0.33) LMNAMAPTHTTTSHRPOLB
SCHEMBL11348171 1.00 LMNA (0.33) LMNAMAPTHTTTSHRPOLB
SCHEMBL11217037 1.00 LMNA (0.33) LMNAMAPTHTTTSHRPOLB
SCHEMBL11503301 1.00 LMNA (0.33) LMNAMAPTHTTTSHRPOLB
SCHEMBL10828081 0.86 HPGD (0.34) LMNAMAPTHTTTSHRPOLB
SCHEMBL10832189 0.86 HPGD (0.34) LMNAMAPTHTTTSHRPOLB
SCHEMBL10483036 0.86 HPGD (0.34) LMNAMAPTHTTTSHRPOLB
SCHEMBL11173404 0.86 LMNA (0.35) LMNAMAPTHTTTSHRPOLB
SCHEMBL9520759 0.84 LMNA (0.43) LMNATSHRTDP1NPSR1
SCHEMBL11292470 0.84 LMNA (0.43) LMNATSHRTDP1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0414059-B1 Dihalogenovinylbenzylesters, process and starting material for their preparation and their utilization for the control of parasites BASF AG (DE) 1993-10-27 EP disclosed
EP-0347693-B1 BENZONITRILES, BENZALDEHYDES AND BENZYL ALCOHOLS, AND PROCESSES FOR THEIR PRODUCTION BASF Aktiengesellschaft (DE) 1992-09-09 EP disclosed
EP-0347694-B1 PYRETHROIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATING PESTS BASF Aktiengesellschaft (DE) 1992-08-26 EP disclosed
EP-0414059-A1 Dihalogenovinylbenzylesters, process and starting material for their preparation and their utilization for the control of parasites BASF Aktiengesellschaft (DE) 1991-02-27 EP disclosed
EP-0347694-A1 Pyrethroids, process for their preparation and their use in combating pests BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
EP-0347693-A1 Benzonitriles, benzaldehydes and benzyl alcohols, and processes for their production BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
EP-0034731-B1 TRIFLUOROMETHYLBENZYLIC ESTERS, THEIR INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES BAYER AG (DE) 1985-10-30 EP disclosed
EP-0022971-B1 PROCESS FOR THE PREPARATION OF 3-(2,2-DICHLOROVINYL)-2,2-DIMETHYL-CYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES BAYER AG (DE) 1983-03-16 EP disclosed
EP-0022984-B1 PROCESS FOR THE PREPARATION OF DERIVATIVES OF 3-(2.2-DICHLORO-VINYL)-2.2-DIMETHYL-CYCLOPROPANE-1-CARBOXYLIC ACID BAYER AG (DE) 1982-01-13 EP disclosed
EP-0012722-B1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 3-SUBSTITUTED 2-(2',2'-DIHALOVINYL)-CYCLOPROPANE-1-CARBOXYLIC ACIDS AND THEIR DERIVATIVES; 4-(2',2',2'-TRIHALOETHYL)-CYCLOBUTANE-1-SULPHONIC ACID SALTS AND THEIR PREPARATION CIBA-GEIGY AG (CH) 1981-12-09 EP disclosed
EP-0001980-B1 PROCESS FOR THE PREPARATION OF HALOGENOVINYL-GAMMA-BUTYROLACTONES, INTERMEDIATES THEREFOR AND THEIR PREPARATION BAYER AG (DE) 1981-05-06 EP disclosed
EP-0022984-A1 Process for the preparation of derivatives of 3-(2.2-dichloro-vinyl)-2.2-dimethyl-cyclopropane-1-carboxylic acid BAYER AG (DE) 1981-01-28 EP disclosed
EP-0022971-A1 Process for the preparation of 3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid derivatives BAYER AG (DE) 1981-01-28 EP disclosed
EP-0022971-A1 Process for the preparation of 3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid derivatives BAYER AG (DE) 1981-01-28 EP disclosed
EP-0012722-A1 Process for the preparation of optically active 3-substituted 2-(2',2'-dihalovinyl)-cyclopropane-1-carboxylic acids and their derivatives; 4-(2',2',2'-trihaloethyl)-cyclobutane-1-sulphonic acid salts and their preparation CIBA-GEIGY AG (CH) 1980-06-25 EP disclosed