Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292470 | 1.00 | LMNA (0.43) | LMNAALOX15CYP1A2CYP2C19TSHR | |
| SCHEMBL1325683 | 0.86 | LMNA (0.44) | LMNAALOX15CYP1A2CYP2C19TSHR | |
| SCHEMBL8584924 | 0.86 | LMNA (0.44) | LMNAALOX15CYP1A2CYP2C19TSHR | |
| SCHEMBL11503301 | 0.84 | LMNA (0.33) | LMNATSHRTDP1NPSR1 | |
| SCHEMBL9520258 | 0.84 | LMNA (0.33) | LMNATSHRTDP1NPSR1 | |
| SCHEMBL11382005 | 0.84 | LMNA (0.33) | LMNATSHRTDP1NPSR1 | |
| SCHEMBL11348171 | 0.84 | LMNA (0.33) | LMNATSHRTDP1NPSR1 | |
| SCHEMBL11217037 | 0.84 | LMNA (0.33) | LMNATSHRTDP1NPSR1 | |
| SCHEMBL9519346 | 0.82 | LMNA (0.32) | LMNA | |
| SCHEMBL9518850 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414059-B1 | Dihalogenovinylbenzylesters, process and starting material for their preparation and their utilization for the control of parasites | BASF AG (DE) | 1993-10-27 | — | — | EP | disclosed |
| EP-0347694-B1 | PYRETHROIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATING PESTS | BASF Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | disclosed |
| EP-0414059-A1 | Dihalogenovinylbenzylesters, process and starting material for their preparation and their utilization for the control of parasites | BASF Aktiengesellschaft (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0347694-A1 | Pyrethroids, process for their preparation and their use in combating pests | BASF Aktiengesellschaft (DE) | 1989-12-27 | — | — | EP | disclosed |
| EP-0020988-A2 | Process for preparing alpha-cyano-benzyl esters; intermediates therefor and their preparation | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |