SCHEMBL15345209

SCHEMBL15345209

O=C(O)CCCCC(=O)S

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.69
TSHR P16473 5/20 0.65
NFKB1 P19838 2/20 0.65
PMP22 Q01453 1/20 0.65
FOLH1 Q04609 1/20 0.60
SLC22A6 Q4U2R8 2/20 0.59
GPR84 Q9NQS5 5/20 0.52
FFAR1 O14842 2/20 0.52
FFAR4 Q5NUL3 2/20 0.52
AKR1B1 P15121 1/20 0.52
CYP2D6 P10635 1/20 0.52
PPARG P37231 6/20 0.50
PPARD Q03181 6/20 0.50
PPARA Q07869 6/20 0.50
HDAC11 Q96DB2 5/20 0.50
ALDH1A1 P00352 2/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
FABP4 P15090 2/20 0.50
PTPN1 P18031 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18869613 0.97 TSHR (0.71) LMNATSHRNFKB1PMP22FOLH1
SCHEMBL10714917 0.97 TSHR (0.71) LMNATSHRNFKB1PMP22FOLH1
SCHEMBL14828471 0.94
SCHEMBL11348207 0.87 LMNA (0.44) LMNATSHRNFKB1PMP22FOLH1
SCHEMBL28138992 0.83 TSHR (0.47) LMNATSHRNFKB1PMP22FOLH1
SCHEMBL28065031 0.83 TSHR (0.47) LMNATSHRNFKB1PMP22FOLH1
SCHEMBL27924266 0.83 LMNA (0.41) LMNATSHRNFKB1PMP22FOLH1
SCHEMBL27712598 0.83 TSHR (0.47) LMNATSHRNFKB1PMP22FOLH1
Adipic Acid SCHEMBL2244299 0.83 LMNA (1.00) LMNATSHRNFKB1PMP22FOLH1
Adipic Acid SCHEMBL1330953 0.83 LMNA (1.00) LMNATSHRNFKB1PMP22FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105102465-B It is used to prepare the catalysis process of thiocarboxylate silane 莫门蒂夫性能材料股份有限公司 2018-11-06 CN claimed
CN-105102465-B It is used to prepare the catalysis process of thiocarboxylate silane 莫门蒂夫性能材料股份有限公司 2018-11-06 CN disclosed
CN-107427612-A Medical devices degradable on demand 耶路撒冷希伯来大学伊森姆研究发展有限公司 2017-12-01 CN disclosed
US-20130280766-A1 HYBRID POLYKETIDE SYNTHASES THE REGENTS OF THE UNVERSITY OF CALIFORNIA (US) 2013-10-24 US disclosed