Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349824 | 0.80 | SMN1; SMN2 (0.48) | MAPK1HSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL1178125 | 0.79 | POLB (0.46) | MAPK1HSD17B10ALDH1A1GAAKMT2A | |
| SCHEMBL1178882 | 0.79 | GAA (0.56) | ALDH1A1GAAMAPTLMNAPOLB | |
| SCHEMBL1178846 | 0.77 | ATM (0.49) | MAPK1HSD17B10ALDH1A1GAAMAPT | |
| SCHEMBL4209923 | 0.77 | LMNA (0.46) | MAPK1HSD17B10GAAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL4203364 | 0.75 | ATM (0.48) | ALDH1A1GAAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4206022 | 0.75 | LMNA (0.47) | MAPK1HSD17B10GAAMAPTMEN1 | |
| SCHEMBL1178410 | 0.74 | ATM (0.41) | MAPK1HSD17B10ALDH1A1GAAMAPT | |
| SCHEMBL1178797 | 0.74 | RAB9A (0.43) | GAAMAPTLMNAPOLBCYP2D6 | |
| SCHEMBL1178929 | 0.74 | ATM (0.50) | MAPK1HSD17B10ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001947-B1 | 2-AMINO-THIAZOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL PREPARATIONS | INSTITUT MERIEUX (FR) | 1981-10-14 | — | — | EP | claimed |