Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 3/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.50 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | FGF1 | P05230 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907776 | 0.92 | TIMP3 (0.50) | TIMP3CASP6CTDSP1TNNI3TNNT2 | |
| SCHEMBL10629458 | 0.90 | TNNI3 (0.58) | TIMP3TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL11342482 | 0.89 | TIMP3 (0.59) | TIMP3TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL11426191 | 0.88 | CASP6 (0.65) | TIMP3CASP6CTDSP1TNNI3TNNT2 | |
| SCHEMBL11440913 | 0.85 | CASP6 (0.63) | TIMP3CASP6CTDSP1TNNI3TNNT2 | |
| SCHEMBL11347423 | 0.85 | TIMP3 (0.54) | TIMP3CASP6CTDSP1ENPP2PRMT1 | |
| SCHEMBL11338942 | 0.85 | HPSE (0.52) | TIMP3CASP6CTDSP1TNNI3TNNT2 | |
| SCHEMBL11433801 | 0.84 | CD40 (0.61) | CASP6MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL11350653 | 0.83 | TIMP3 (0.55) | TIMP3CASP6CTDSP1ENPP2PRMT1 | |
| SCHEMBL11349822 | 0.83 | TNNI3 (0.46) | TIMP3TNNI3TNNT2TNNC1HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297372-A | ANTIARTHRITIC AGENTS; COLLAGENASE AND PROTEOLYTIC ENZYME INHIBITORS; BONE, SKIN, AND ORAL DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4216164-A | Ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |