SCHEMBL11348357

SCHEMBL11348357

CS(=O)(=O)c1ncc(OC(=O)Cl)c(Cl)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 10/20 0.46
MAPT P10636 10/20 0.46
TLR9 Q9NR96 7/20 0.46
NPC1 O15118 5/20 0.46
ALDH1A1 P00352 4/20 0.46
NPSR1 Q6W5P4 4/20 0.46
HTT P42858 3/20 0.46
XBP1 P17861 3/20 0.46
MAPK1 P28482 2/20 0.46
HSD17B10 Q99714 1/20 0.46
RAB9A P51151 4/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
AGTR1 P30556 2/20 0.38
LMNA P02545 5/20 0.36
SMN1; SMN2 Q16637 5/20 0.36
MITF O75030 2/20 0.36
S1PR4 O95977 2/20 0.36
PKM P14618 1/20 0.36
PAX8 Q06710 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10354639 0.88 MAPT (0.46) TP53MAPTTLR9NPC1ALDH1A1
SCHEMBL11345023 0.84 TP53 (0.43) TP53MAPTTLR9NPC1ALDH1A1
SCHEMBL1442168 0.80 MAPT (0.43) TP53MAPTTLR9NPC1ALDH1A1
SCHEMBL10481948 0.79 MAPT (0.46) TP53MAPTTLR9NPC1ALDH1A1
SCHEMBL9626014 0.77 ALDH1A1 (0.33) MAPTNPC1ALDH1A1RAB9AMEN1
SCHEMBL7087131 0.76 NFKB1 (0.37) ALDH1A1SMN1; SMN2
SCHEMBL333877 0.76 TP53 (0.46) TP53MAPTTLR9NPC1ALDH1A1
Hydrochloric Acid SCHEMBL11488412 0.74 TP53 (0.44) TP53MAPTTLR9NPC1ALDH1A1
SCHEMBL11266182 0.73 MEN1 (0.47) MAPTNPC1ALDH1A1MEN1KMT2A
SCHEMBL9626897 0.73 TP53 (0.41) TP53MAPTTLR9NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0001451-B1 WATER-SOLUBLE AZO-PHTHALOCYANINE FIBRE-REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-09-23 EP disclosed
EP-0001629-B1 WATER-SOLUBLE, FIBRE-REACTIVE, GREEN AZO-PHTHALOCYANINE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-08-12 EP disclosed
EP-0001614-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their application, as well as the phthalocyanine pyrazolone intermediates and their preparation CASSELLA Aktiengesellschaft (DE) 1979-05-02 EP disclosed
EP-0001629-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-05-02 EP disclosed