SCHEMBL9626014

SCHEMBL9626014

Cc1ncc(OC(=O)Cl)c(Cl)n1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 1/20 0.33
NTRK1 P04629 1/20 0.33
HCRTR1 O43613 1/20 0.32
HCRTR2 O43614 1/20 0.32
HSP90AA1 P07900 2/20 0.32
KMT2A Q03164 5/20 0.31
L3MBTL1 Q9Y468 4/20 0.31
MAPT P10636 3/20 0.31
MEN1 O00255 3/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
CYP2D6 P10635 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PLA2G1B P04054 1/20 0.31
POLB P06746 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31
HSP90AB1 P08238 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10695297 0.86 NTRK1 (0.36) ALDH1A1KDM4ENTRK1HCRTR1HCRTR2
SCHEMBL5501359 0.86 KDM4E (0.41) ALDH1A1KDM4EKMT2AL3MBTL1MAPT
SCHEMBL7087131 0.81 NFKB1 (0.37) ALDH1A1KDM4E
SCHEMBL11266182 0.78 MEN1 (0.47) ALDH1A1KDM4EKMT2AL3MBTL1MAPT
SCHEMBL11348357 0.77 TP53 (0.46) ALDH1A1KMT2AL3MBTL1MAPTMEN1
SCHEMBL10585289 0.76 ALDH1A1 (0.38) ALDH1A1KDM4ENTRK1HSP90AA1KMT2A
SCHEMBL9626746 0.75 NFKB1 (0.41) ALDH1A1KDM4EKMT2AL3MBTL1MAPT
SCHEMBL351851 0.75 MAPT (0.49) ALDH1A1KDM4EKMT2AL3MBTL1MAPT
SCHEMBL11293818 0.74 MAPT (0.44) ALDH1A1KMT2AL3MBTL1MAPTMEN1
SCHEMBL12123836 0.72 POLB (0.46) ALDH1A1KDM4ENTRK1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0321784-B1 FORMAZANE DYES CONTAINING HEAVY METALS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS BAYER AG (DE) 1992-03-18 EP disclosed
EP-0255890-B1 PROCESS FOR THE REACTION OF AMINES WITH HETEROCYCLIC REACTIVE COMPOUNDS BAYER AG (DE) 1990-08-29 EP disclosed
EP-0321784-A2 Formazane dyes containing heavy metals, process for their preparation and their use in dyeing and printing fibrous materials BAYER AG (DE) 1989-06-28 EP disclosed
EP-0151792-B1 REACTION OF AMINES WITH HETEROCYCLIC REACTIVE COMPOUNDS BAYER AG (DE) 1988-11-30 EP disclosed
EP-0158882-B1 TRIPHENEDIOXAZINE DYES BAYER AG (DE) 1987-12-16 EP disclosed
EP-0097289-B1 AZO DYESTUFFS BAYER AG (DE) 1986-10-15 EP disclosed
EP-0177978-A2 Naphthol amine derivatives BAYER AG (DE) 1986-04-16 EP disclosed
EP-0158882-A2 Triphenedioxazine dyes BAYER AG (DE) 1985-10-23 EP disclosed
EP-0151792-A2 Reaction of amines with heterocyclic reactive compounds BAYER AG (DE) 1985-08-21 EP disclosed
EP-0128316-A1 Reactive disazo dyes BAYER AG (DE) 1984-12-19 EP disclosed
EP-0013936-B1 REACTIVE AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE IN DYEING MATERIALS CONTAINING HYDROXYL GROUPS AND AMIDE GROUPS BAYER AG (DE) 1982-09-22 EP disclosed
EP-0021372-B1 COPPER COMPLEXES OF DISAZO REACTIVE DYESTUFFS BAYER AG (DE) 1982-07-07 EP disclosed
EP-0053320-A2 Process for the preparation of phthalocyanin compounds BAYER AG (DE) 1982-06-09 EP disclosed
EP-0050266-A1 Reactive disazo dyes, process for their preparation and their use in dyeing and printing materials that contain hydroxyl and/or nitrogen BAYER AG (DE) 1982-04-28 EP disclosed
EP-0047863-A2 Reactive phthalocyanine hyes, process for their preparation and their use in dyeing materials containing hydroxyle groups and/or nitrogen BAYER AG (DE) 1982-03-24 EP disclosed
EP-0001451-B1 WATER-SOLUBLE AZO-PHTHALOCYANINE FIBRE-REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-09-23 EP disclosed
EP-0001629-B1 WATER-SOLUBLE, FIBRE-REACTIVE, GREEN AZO-PHTHALOCYANINE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-08-12 EP disclosed
EP-0001614-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their application, as well as the phthalocyanine pyrazolone intermediates and their preparation CASSELLA Aktiengesellschaft (DE) 1979-05-02 EP disclosed
EP-0001629-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-05-02 EP disclosed
EP-0001451-A1 Water-soluble azo-phthalocyanine fibre-reactive dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-04-18 EP disclosed