Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11366338 | 0.88 | LMNA (0.45) | LMNAMAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL11360035 | 0.85 | PPARG (0.51) | LMNAMAPTRAB9AL3MBTL1PTGES | |
| SCHEMBL18322706 | 0.76 | IRAK4 (0.55) | LMNAMAPTRAB9ATAS1R3TAS1R1 | |
| SCHEMBL28490552 | 0.76 | PPARG (0.49) | PTGESALOX5PPARGPPARATDP1 | |
| SCHEMBL8935703 | 0.76 | SMN1; SMN2 (0.54) | LMNAMAPTRAB9AL3MBTL1PTGES | |
| SCHEMBL8935705 | 0.76 | SMN1; SMN2 (0.54) | LMNAMAPTRAB9AL3MBTL1PTGES | |
| SCHEMBL28586752 | 0.76 | PPARG (0.48) | LMNAMAPTL3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL15397124 | 0.75 | TDP1 (0.43) | LMNAL3MBTL1TDP1TP53CYP3A4 | |
| SCHEMBL20847870 | 0.75 | HTR1B (0.40) | MAPTPTGESALOX5PPARGPPARA | |
| SCHEMBL4904732 | 0.75 | MAPT (0.42) | LMNAMAPTRAB9AL3MBTL1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011596-B1 | 2-(ALPHA-PHENOXY-ALKYL)-IMIDAZOLINES AND THEIR SALTS, THEIR PREPARATION AND USE, AND AGENTS AGAINST PHYTOPARASITIC AND ZOOPARASITIC MITES CONTAINING THEM | CIBA-GEIGY AG (CH) | 1981-12-30 | — | — | EP | disclosed |
| US-4276302-A | PARASITICIDES | CIBA-GEIGY CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |
| EP-0011596-A1 | 2-(Alpha-phenoxy-alkyl)-imidazolines and their salts, their preparation and use, and agents against phytoparasitic and zooparasitic mites containing them | CIBA-GEIGY AG (CH) | 1980-05-28 | — | — | EP | disclosed |
| EP-0011596-A1 | 2-(Alpha-phenoxy-alkyl)-imidazolines and their salts, their preparation and use, and agents against phytoparasitic and zooparasitic mites containing them | CIBA-GEIGY AG (CH) | 1980-05-28 | — | — | EP | disclosed |