Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348367 | 0.88 | LMNA (0.43) | LMNAMAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8935703 | 0.84 | SMN1; SMN2 (0.54) | LMNAMAPTRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL8935705 | 0.84 | SMN1; SMN2 (0.54) | LMNAMAPTRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL4904732 | 0.83 | MAPT (0.42) | LMNAMAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL31560857 | 0.77 | ALDH1A1 (0.49) | LMNAMAPTRAB9AALDH1A1GAA | |
| SCHEMBL29213724 | 0.76 | TDP1 (0.54) | L3MBTL1ALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL11360035 | 0.76 | PPARG (0.51) | LMNAMAPTRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL11806989 | 0.75 | POLB (0.41) | LMNAMAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL14121887 | 0.74 | LMNA (0.47) | LMNAMAPTL3MBTL1GAATSHR | |
| SCHEMBL14122548 | 0.74 | LMNA (0.47) | LMNAMAPTL3MBTL1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276302-A | PARASITICIDES | CIBA-GEIGY CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |