Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.35 |
| ▸ | TLR4 | O00206 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214607 | 0.86 | FSCN1 (0.45) | NR1H3ALDH1A1GAA | |
| SCHEMBL11341883 | 0.84 | HSD11B1 (0.41) | KMT2ANR1H3NPC1ALDH1A1LMNA | |
| SCHEMBL11343561 | 0.81 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11216284 | 0.81 | MEN1 (0.31) | KMT2ANR1H3MEN1 | |
| SCHEMBL11339893 | 0.80 | EPAS1 (0.31) | KMT2AMEN1 | |
| SCHEMBL11336549 | 0.75 | ALDH1A1 (0.45) | GPBAR1ALDH1A1LMNA | |
| SCHEMBL11339322 | 0.75 | MAPT (0.50) | KMT2AALDH1A1MEN1 | |
| SCHEMBL11345629 | 0.74 | NR1I2 (0.36) | KMT2AHPGDNR1H3ALDH1A1 | |
| SCHEMBL11331890 | 0.71 | VCAM1 (0.37) | ALOX15HPGDALDH1A1 | |
| SCHEMBL11335375 | 0.71 | MEN1 (0.31) | KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010844-B1 | NOVEL N,N'-BIS(TRIFLUOROMETHYLSULFONYL)OXAMIDES, CHEMILUMINESCENT COMPOSITIONS CONTAINING THEM AND PROCESSES FOR GENERATING CHEMILUMINESCENCE EMPLOYING SAID COMPOSITIONS | AMERICAN CYANAMID COMPANY (US) | 1981-10-07 | — | — | EP | disclosed |
| US-4226738-A | SUPERIOR LIGHT INTENSITY, QUANTUM EFFICIENT, AND LONG-LASTING | AMERICAN CYANAMID COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0010844-A1 | Novel N,N'-bis(trifluoromethylsulfonyl)oxamides, chemiluminescent compositions containing them and processes for generating chemiluminescence employing said compositions | AMERICAN CYANAMID COMPANY (US) | 1980-05-14 | — | — | EP | disclosed |