Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278699 | 0.81 | OPRM1 (0.53) | OPRM1OPRL1ALDH1A1TSHRAOC3 | |
| SCHEMBL10708855 | 0.80 | OPRM1 (0.51) | OPRM1OPRL1ALDH1A1TSHRAOC3 | |
| SCHEMBL27875481 | 0.77 | OPRM1 (0.49) | OPRM1OPRL1ALDH1A1TSHRAOC3 | |
| SCHEMBL9768588 | 0.76 | TAAR1 (0.52) | OPRM1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3241413 | 0.75 | OPRM1 (0.50) | OPRM1OPRL1ALDH1A1TSHRAOC3 | |
| SCHEMBL24434663 | 0.75 | OPRM1 (0.58) | OPRM1OPRL1ALDH1A1TSHRAOC3 | |
| SCHEMBL24434872 | 0.70 | OPRM1 (0.53) | OPRM1OPRL1ALDH1A1TSHRAOC3 | |
| SCHEMBL3915316 | 0.70 | OPRM1 (0.45) | OPRM1OPRL1ALDH1A1TSHRAOC3 | |
| SCHEMBL2464748 | 0.69 | OPRM1 (0.64) | OPRM1OPRL1ALDH1A1TSHRSLC6A2 | |
| SCHEMBL3409019 | 0.69 | OPRL1 (1.00) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268455-A | Chelating tertiary amino metal amides | EXXON RESEARCH & ENGINEERING CO. (US) | 1981-05-19 | — | — | US | disclosed |