Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26986036 | 0.81 | OPRM1 (0.49) | OPRM1OPRL1TSHRALDH1A1ADRA2B | |
| SCHEMBL26985915 | 0.75 | L3MBTL1 (0.52) | OPRM1OPRL1ALDH1A1OPRK1MEN1 | |
| SCHEMBL24434663 | 0.75 | OPRM1 (0.58) | OPRM1OPRL1TSHRALDH1A1ADRA2B | |
| SCHEMBL3915316 | 0.74 | OPRM1 (0.45) | OPRM1OPRL1TSHRALDH1A1ADRA2B | |
| SCHEMBL11348690 | 0.70 | OPRM1 (0.53) | OPRM1OPRL1TSHRALDH1A1ADRA2B | |
| SCHEMBL9278699 | 0.70 | OPRM1 (0.53) | OPRM1OPRL1TSHRALDH1A1SLC6A2 | |
| SCHEMBL3409019 | 0.69 | OPRL1 (1.00) | OPRM1OPRL1OPRK1 | |
| SCHEMBL15111158 | 0.69 | OPRM1 (0.51) | OPRM1OPRL1TSHRALDH1A1AOC3 | |
| SCHEMBL10708855 | 0.69 | OPRM1 (0.51) | OPRM1OPRL1TSHRALDH1A1SLC6A2 | |
| SCHEMBL18756363 | 0.68 | TSHR (0.54) | OPRM1OPRL1TSHRALDH1A1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | OPRM1 4412/4885OPRL1 3554/4885TSHR 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.