Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 8/20 | 0.62 |
| ▸ | DRD4 | P21917 | 8/20 | 0.62 |
| ▸ | DRD3 | P35462 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 7/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352668 | 0.98 | TSHR (0.67) | TSHRDRD2DRD4DRD3KDM4E | |
| Hydrochloric Acid SCHEMBL28934886 | 0.89 | DRD2 (0.73) | DRD2DRD4DRD3ESR1LTA4H | |
| Hydrochloric Acid SCHEMBL11649275 | 0.89 | DRD2 (0.73) | DRD2DRD4DRD3ESR1LTA4H | |
| Bromide SCHEMBL6578004 | 0.89 | DRD2 (0.73) | DRD2DRD4DRD3ESR1LTA4H | |
| Bromide SCHEMBL11558499 | 0.89 | DRD2 (0.73) | DRD2DRD4DRD3ESR1LTA4H | |
| SCHEMBL7991599 | 0.89 | DRD2 (0.79) | DRD2DRD4DRD3ESR1LTA4H | |
| Nitrogen SCHEMBL8486432 | 0.86 | DRD2 (0.62) | DRD2DRD4DRD3ESR1LTA4H | |
| SCHEMBL23067904 | 0.85 | DRD4 (0.70) | TSHRDRD2DRD4DRD3KDM4E | |
| SCHEMBL31650955 | 0.85 | DRD4 (0.70) | TSHRDRD2DRD4DRD3KDM4E | |
| SCHEMBL9447177 | 0.85 | LTA4H (0.71) | DRD2DRD4DRD3ESR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018884-B1 | PROCESS FOR THE PREPARATION OF TRIS(ETHER AMINES) AND SO OBTAINED TRIS(ETHER AMINES) | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-11-04 | — | — | EP | claimed |