SCHEMBL7991599

SCHEMBL7991599

CCCCCNCCOc1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 12/20 0.79
DRD4 P21917 12/20 0.79
DRD3 P35462 9/20 0.79
KMT2A Q03164 1/20 0.62
LTA4H P09960 2/20 0.61
HTR1B P28222 1/20 0.59
GAA P10253 1/20 0.59
ESR1 P03372 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28934886 0.97 DRD2 (0.73) DRD2DRD4DRD3KMT2ALTA4H
Bromide SCHEMBL6578004 0.97 DRD2 (0.73) DRD2DRD4DRD3KMT2ALTA4H
Hydrochloric Acid SCHEMBL11649275 0.97 DRD2 (0.73) DRD2DRD4DRD3KMT2ALTA4H
Bromide SCHEMBL11558499 0.97 DRD2 (0.73) DRD2DRD4DRD3KMT2ALTA4H
SCHEMBL21453106 0.95 DRD2 (0.81) DRD2DRD4DRD3KMT2ALTA4H
SCHEMBL9447177 0.92 LTA4H (0.71) DRD2DRD4DRD3LTA4HESR1
SCHEMBL11352668 0.90 TSHR (0.67) DRD2DRD4DRD3KMT2ALTA4H
Nitrogen SCHEMBL8486432 0.90 DRD2 (0.62) DRD2DRD4DRD3KMT2ALTA4H
SCHEMBL16606096 0.89 DRD2 (0.78) DRD2DRD4DRD3KMT2ALTA4H
SCHEMBL11348787 0.89 TSHR (0.65) DRD2DRD4DRD3LTA4HESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001036363-A1 PROCESS FOR PREPARING ACYLAROMATIC COMPOUNDS CATALYTICA PHARMACEUTICALS, INC. (US) 2001-05-25 WO claimed
WO-2001036363-A1 PROCESS FOR PREPARING ACYLAROMATIC COMPOUNDS CATALYTICA PHARMACEUTICALS, INC. (US) 2001-05-25 WO disclosed