Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KHK | P50053 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.47 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.45 |
| ▸ | WNT3A | P56704 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11382277 | 0.99 | GHSR (0.49) | GHSRCHRM2CHRM1CHRM3CES2 | |
| SCHEMBL465887 | 0.84 | RELA (0.47) | GHSRKHK | |
| SCHEMBL11343167 | 0.79 | KHK (0.52) | GHSRCES1KHKMEN1KMT2A | |
| Bromide SCHEMBL11099888 | 0.78 | CHRM2 (0.49) | CHRM2CHRM1CHRM3CES2CES1 | |
| SCHEMBL21848527 | 0.76 | KHK (0.45) | KHK | |
| SCHEMBL11164963 | 0.76 | CTNNB1 (0.47) | CHRM2CHRM1CHRM3CES2CES1 | |
| SCHEMBL29039262 | 0.75 | CHRNB4 (0.63) | CHRNB4CHRNA3 | |
| SCHEMBL26999492 | 0.75 | CHRNB4 (0.63) | CHRNB4CHRNA3 | |
| SCHEMBL11807455 | 0.75 | MEN1 (0.49) | MEN1KMT2ACHRNB4CHRNA3HSD11B1 | |
| SCHEMBL7860033 | 0.75 | POLB (0.54) | KHKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002672-B1 | SUBSTITUTED PYRROLIDINES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-08-26 | — | — | EP | disclosed |
| US-4198424-A | ANALGESICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-04-15 | — | — | US | disclosed |
| EP-0002672-A2 | Substituted pyrrolidines, process for their preparation and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1979-07-11 | — | — | EP | disclosed |