Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11414581 | 0.85 | TAAR1 (0.44) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11341543 | 0.83 | TRPA1 (0.47) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4086277 | 0.79 | EPHX1 (0.43) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11345081 | 0.78 | SIGMAR1 (0.42) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4082647 | 0.78 | EPHX1 (0.41) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4084733 | 0.78 | EPHX1 (0.41) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2098592 | 0.77 | SIGMAR1 (0.52) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11350285 | 0.76 | CSNK1E (0.47) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13302616 | 0.75 | TAAR1 (0.50) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11429740 | 0.74 | CSNK1E (0.54) | SIGMAR1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000614-B1 | PRODUCTION OF DICHLOROSILANE DERIVATIVES | Chisso Corporation (JP) | 1981-11-25 | — | — | EP | disclosed |
| US-4242272-A | Substituted phenethyldichlorosilanes and method for producing same | CHISSO CORPORATION (JP) | 1980-12-30 | — | — | US | disclosed |