Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641597 | 0.85 | HRH1 (0.44) | — | |
| SCHEMBL11336356 | 0.83 | LMNA (0.41) | RIPK1HTR1ALMNAIDO1KDM4E | |
| SCHEMBL8483117 | 0.80 | IDO1 (0.42) | HTR1ALMNAIDO1KDM4EL3MBTL1 | |
| SCHEMBL11347494 | 0.79 | CYP19A1 (0.39) | KDM4E | |
| SCHEMBL9119383 | 0.79 | CYP19A1 (0.43) | — | |
| Oxalic Acid SCHEMBL5154647 | 0.78 | KDM4E (0.38) | LMNAIDO1KDM4EL3MBTL1CYP2D6 | |
| SCHEMBL9728465 | 0.78 | CYP19A1 (0.43) | CYP2D6 | |
| SCHEMBL9122156 | 0.77 | HRH1 (0.42) | — | |
| SCHEMBL9728379 | 0.77 | CYP19A1 (0.42) | — | |
| SCHEMBL9728037 | 0.77 | CYP19A1 (0.55) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034473-A2 | Substituted imidazoles, their preparation and pharmaceutical compositions containing the same | Farmos-Yhtyma Oy (FI) | 1981-08-26 | — | — | EP | disclosed |