Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728379 | 0.90 | CYP19A1 (0.42) | CYP19A1SLC6A4SLC6A2SLC6A3CYSLTR2 | |
| SCHEMBL9123062 | 0.90 | CYP19A1 (0.46) | CYP19A1ACP3SLC6A4KCNH2ANPEP | |
| SCHEMBL9641597 | 0.82 | HRH1 (0.44) | CYP19A1 | |
| SCHEMBL9120160 | 0.81 | CYP19A1 (0.45) | CYP19A1SLC6A4SLC6A2SLC6A3CYSLTR2 | |
| SCHEMBL9190554 | 0.81 | CYP19A1 (0.59) | CYP19A1SLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL1753940 | 0.80 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL4382434 | 0.78 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL11348998 | 0.78 | DHFR (0.44) | CYP2D6 | |
| SCHEMBL1538332 | 0.78 | CYP19A1 (0.54) | CYP19A1ACP3SLC6A4KCNH2ANPEP | |
| SCHEMBL8105600 | 0.78 | CYP19A1 (0.36) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098923-A | Antiestrogens, anticarcinogenic agents or fungicides | FARMOS-YHTYMA OY (FI) | 1992-03-24 | — | — | US | disclosed |