Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336356 | 0.94 | LMNA (0.41) | KDM4ELMNAL3MBTL1CYP2D6IDO1 | |
| SCHEMBL9727813 | 0.79 | SLC6A4 (0.40) | KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL11348998 | 0.78 | DHFR (0.44) | KDM4ELMNAL3MBTL1CYP2D6IDO1 | |
| SCHEMBL11339982 | 0.78 | NR3C2 (0.40) | SMN1; SMN2NPC1RAB9AKMT2ACYP2D6 | |
| Oxalic Acid SCHEMBL5155135 | 0.78 | NOS2 (0.34) | PTPRA | |
| SCHEMBL5154658 | 0.77 | PABPC1 (0.34) | PTPRAKMT2ACYP2D6 | |
| SCHEMBL8483117 | 0.75 | IDO1 (0.42) | KDM4ELMNAL3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL30280698 | 0.74 | GRIN2D (0.57) | — | |
| SCHEMBL10551331 | 0.74 | MAOA (0.44) | ALDH1A1 | |
| SCHEMBL1312465 | 0.74 | PTPRA (0.50) | SMN1; SMN2PTPRACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472232-B1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORP (KR) | 2007-01-24 | — | — | EP | disclosed |
| EP-1472232-A4 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORP (KR) | 2006-02-01 | — | — | EP | disclosed |
| EP-1472232-A1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | Yuhan Corporation (KR) | 2004-11-03 | — | — | EP | disclosed |
| US-6706888-B2 | REACTING A 3-HALOTETRAHYDROFURAN OR TETRAHYDROPYRAN COMPOUND WITH FORMAMIDINE OR ITS SALT IN THE PRESENCE OF A BASE TO PRODUCE A 3-(1H-IMIDAZOL-4-YL)PROPANOL DERIVATIVE; EFFICIENCY; INTERMEDIATES; ANTICARCINOGENIC AGENTS; VIRICIDES; | YUHAN CORPORATION (KR) | 2004-03-16 | — | — | US | disclosed |
| US-20030153769-A1 | Processes for preparing imidazole derivatives and salts thereof | YUHAN CORPORATION | 2003-08-14 | — | — | US | disclosed |
| WO-2003066600-A1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORPORATION (KR) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153769-A1 | Processes for preparing imidazole derivatives and salts thereof | NISCH, INF2, SRI | KDM4E 3004/4885BCAT2 1007/4885LMNA 3075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.