Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966022 | 0.85 | MAOB (0.52) | MAOBALDH1A1HTTHPGDTSHR | |
| SCHEMBL37410 | 0.80 | MAOB (0.54) | MAOBALDH1A1HTTHPGDTSHR | |
| SCHEMBL30605656 | 0.80 | MAOB (0.54) | MAOBALDH1A1HTTHPGDTSHR | |
| SCHEMBL286962 | 0.80 | MAOB (0.56) | MAOBALDH1A1HTTHPGDTSHR | |
| SCHEMBL602067 | 0.79 | MAOB (0.55) | MAOBALDH1A1HTTHPGDTSHR | |
| SCHEMBL602068 | 0.79 | MAOB (0.55) | MAOBALDH1A1HTTHPGDTSHR | |
| SCHEMBL5932809 | 0.79 | MAOB (0.55) | MAOBALDH1A1HTTHPGDTSHR | |
| SCHEMBL1556056 | 0.77 | MAOB (0.54) | MAOBALDH1A1HTTHPGDTSHR | |
| SCHEMBL258506 | 0.77 | ALDH1A1 (0.56) | MAOBALDH1A1HTTHPGDTSHR | |
| SCHEMBL20598466 | 0.77 | MAOB (0.54) | MAOBALDH1A1HTTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292427-A | BACTERICIDES | MERCK & CO., INC. (US) | 1981-09-29 | — | — | US | disclosed |
| US-4210750-A | BY TREATMENT OF 3-HYDROXYMETHYL DERIVATIVE WITH TRIFLUOROACETYL ISOCYANATE | MERCK & CO., INC. (US) | 1980-07-01 | — | — | US | disclosed |