SCHEMBL602068

SCHEMBL602068

O=C(O)OCc1ccccc1[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.55
ALDH1A1 P00352 7/20 0.53
TSHR P16473 1/20 0.53
HTT P42858 1/20 0.53
HPGD P15428 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
KDM4A O75164 1/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL602067 1.00 MAOB (0.55) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL286962 0.88 MAOB (0.56) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL26343373 0.87 MAOB (0.52) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL5932809 0.86 MAOB (0.55) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL4277060 0.85 PPARG (0.55) MAOBALDH1A1TSHRHTTHPGD
Acetic Acid SCHEMBL1357849 0.85 MAOB (0.58) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL258506 0.85 ALDH1A1 (0.56) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL6324821 0.85 MAOB (0.54) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL11009579 0.85 MAOB (0.54) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL20598466 0.85 MAOB (0.54) MAOBALDH1A1TSHRHTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF ZIKANI THERAPEUTICS INC (US) 2026-02-05 US claimed
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US claimed
US-11634449-B2 Macrolides and methods of their preparation and use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-04-25 US claimed
EP-3649135-B1 SYNTHESIS OF HALICHONDRINS HARVARD COLLEGE (US) 2022-12-28 EP claimed
US-20220332747-A1 MACROLIDES AND METHODS OF THEIR PREPARATION AND USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-10-20 US claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
US-11241435-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis THE GENERAL HOSPITAL CORPORATION (US) 2022-02-08 US claimed
EP-3172213-B1 MACROCYCLIC KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2021-09-22 EP claimed
US-20210024919-A1 FUNCTIONALIZED SOLID SUPPORT MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2021-01-28 US claimed
EP-3171874-B1 IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2020-11-18 EP claimed
US-20200256862-A1 FUNCTIONALIZED SOLID SUPPORT MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2020-08-13 US claimed
EP-3063164-B1 SYNTHETIC ROUTE TO 2'-DEOXY-2',2'-DIFLUOROTETRAHYDROURIDINES OTSUKA PHARMA CO LTD (JP) 2018-12-05 EP claimed
EP-2727915-B1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof CONCERT PHARMACEUTICALS INC (US) 2016-04-13 EP claimed
EP-2727915-A1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof Concert Pharmaceuticals Inc. (US) 2014-05-07 EP claimed
US-20100021970-A1 Nucleic Acid Amplification Using a Reversibly Modified Oligonucleotide BI WANLI 2010-01-28 US claimed
EP-2049689-A2 NUCLEIC ACID AMPLIFICATION USING A REVERSIBLY MODIFIED OLIGONUCLEOTIDE Bi, Wanli (US) 2009-04-22 EP claimed
WO-2008016562-A2 NUCLEIC ACID AMPLIFICATION USING A REVERSIBLY MODIFIED OLIGONUCLEOTIDE BI WANLI (US) 2008-02-07 WO claimed
US-12637453-B2 Pyrazolopyridine inhibitors of c-Jun-n-Terminal kinases and uses thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-05-26 US disclosed
EP-0665897-A1 COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1995-08-09 EP disclosed
WO-1994008051-A1 COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1994-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF MALT1, CCR10, CYP51A1 MAOB 2225/4885ALDH1A1 1752/4885TSHR 945/4885
US-20220332747-A1 MACROLIDES AND METHODS OF THEIR PREPARATION AND USE CYP11B2, ERG28, DHCR7 MAOB 969/4885ALDH1A1 1071/4885TSHR 3696/4885
US-11634449-B2 Macrolides and methods of their preparation and use CYP11B2, ERG28, DHCR7 MAOB 969/4885ALDH1A1 1071/4885TSHR 3696/4885
US-11241435-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis SOST, SIK2, SIK1 MAOB 4315/4885ALDH1A1 4790/4885TSHR 1825/4885
US-12637453-B2 Pyrazolopyridine inhibitors of c-Jun-n-Terminal kinases and uses thereof MAP3K1, MAP3K3, MAPK1 MAOB 2000/4885ALDH1A1 1172/4885TSHR 2596/4885
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents ROS1, NOX4, NOX5 MAOB 338/4885ALDH1A1 348/4885TSHR 1680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.