Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16737094 | 0.84 | NPC1 (0.63) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL16737184 | 0.84 | KMT2A (0.63) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL16737187 | 0.84 | PTPN2 (0.51) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL16737107 | 0.84 | PTPN2 (0.51) | PTPN2PTPN1MEN1KMT2AABCC1 | |
| SCHEMBL5804880 | 0.83 | LMNA (0.68) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL16737208 | 0.82 | MAPT (0.49) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL16737137 | 0.82 | AKR1C3 (0.57) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL16737188 | 0.80 | RAB9A (0.53) | PTPN2PTPN1MEN1KMT2AABCC1 | |
| SCHEMBL16737183 | 0.80 | ACLY (0.65) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL16737095 | 0.77 | CDC25B (0.49) | PTPN2PTPN1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012153154-A1 | OXETANE SUBSTITUTED THIENO PYRIMIDINONES | RICHTER GEDEON NYRT. (HU) | 2012-11-15 | — | — | WO | claimed |
| WO-2012153154-A1 | OXETANE SUBSTITUTED THIENO PYRIMIDINONES | RICHTER GEDEON NYRT. (HU) | 2012-11-15 | — | — | WO | disclosed |
| EP-0005559-B1 | PHENYLAMINOTHIOPHENE ACETIC ACIDS, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-11-04 | — | — | EP | disclosed |
| US-4272507-A | Phenylaminothiophenacetic acids, their synthesis, compositions and use | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-06-09 | — | — | US | disclosed |