Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454800 | 0.97 | L3MBTL1 (0.43) | L3MBTL1MLYCDSLC18A3CHRM2CHRM3 | |
| SCHEMBL11350690 | 0.84 | L3MBTL1 (0.41) | L3MBTL1MLYCDSLC18A3CHRM2CHRM3 | |
| SCHEMBL11454799 | 0.81 | OPRM1 (0.41) | L3MBTL1MLYCDCHRM2CHRM3MEN1 | |
| SCHEMBL11331580 | 0.79 | SIGMAR1 (0.41) | MLYCDCHRM2CHRM3MEN1KMT2A | |
| SCHEMBL11333982 | 0.78 | SLC18A3 (0.47) | L3MBTL1MLYCDSLC18A3CHRM2CHRM3 | |
| SCHEMBL11446906 | 0.76 | SIGMAR1 (0.39) | MLYCDCHRM2CHRM3MEN1KMT2A | |
| SCHEMBL11338362 | 0.76 | KDM4E (0.47) | L3MBTL1MLYCDCHRM2CHRM3MEN1 | |
| SCHEMBL11454500 | 0.75 | SLC18A3 (0.46) | L3MBTL1MLYCDSLC18A3CHRM2CHRM3 | |
| SCHEMBL11434873 | 0.74 | CHRM2 (0.42) | MLYCDCHRM2CHRM3MEN1KMT2A | |
| SCHEMBL11333981 | 0.73 | SLC18A3 (0.44) | SLC18A3CHRM2CHRM3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30837-E | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4169156-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-4159339-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4156014-A | N-(2-aminocycloheptyl)alkanoylanilides and in the treatment of depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |