Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 5/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | FCER2 | P06734 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373361 | 1.00 | HPGDS (0.50) | HPGDSPPARGCAPN1CTSBFCER2 | |
| SCHEMBL8765449 | 0.88 | MMP2 (0.53) | PPARGMMP3MMP2MMP7 | |
| SCHEMBL23489850 | 0.88 | MMP2 (0.53) | PPARGMMP3MMP2MMP7 | |
| SCHEMBL1135185 | 0.87 | MME (0.58) | — | |
| SCHEMBL29214532 | 0.87 | MME (0.58) | — | |
| SCHEMBL1135183 | 0.87 | MME (0.58) | — | |
| SCHEMBL8373404 | 0.86 | ACE (0.49) | HPGDSPPARGCA12CA1CA9 | |
| SCHEMBL8373405 | 0.86 | ACE (0.49) | HPGDSPPARGCA12CA1CA9 | |
| SCHEMBL12354114 | 0.86 | HPGDS (0.51) | HPGDSPPARGCAPN1CTSBFCER2 | |
| SCHEMBL13261540 | 0.82 | NOS2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883211-A | Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis | ACLARA BIOSCIENCES, INC. (US) | 1999-03-16 | — | — | US | disclosed |
| WO-1997040078-A1 | THERMOREVERSIBLE HYDROGELS COMPRISING NON-CROSSLINKED COPOLYMERS AND THEIR USE IN ELECTROPHORESIS | SOANE BIOSCIENCES (US) | 1997-10-30 | — | — | WO | disclosed |