Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 14/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 14/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 14/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11346455 | 0.99 | NISCH (0.51) | NISCHADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL545961 | 0.90 | NISCH (0.52) | NISCHADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL11224297 | 0.90 | NISCH (0.54) | NISCHADRA2AADRA2BADRA2CHTR1A | |
| Hydrochloric Acid SCHEMBL9654753 | 0.89 | NISCH (0.53) | NISCHADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL11377087 | 0.88 | ADRA2A (0.52) | NISCHADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL3961636 | 0.88 | NISCH (0.50) | NISCHADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL545845 | 0.83 | NISCH (0.50) | NISCHADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL545847 | 0.83 | NISCH (0.50) | NISCHADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL11369733 | 0.81 | ADRA2A (0.53) | NISCHADRA2AADRA2BADRA2CHTR1A | |
| Hydrochloric Acid SCHEMBL9654915 | 0.79 | NISCH (0.77) | NISCHADRA2AADRA2BADRA2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276302-A | PARASITICIDES | CIBA-GEIGY CORPORATION (US) | 1981-06-30 | — | — | US | claimed |
| EP-0011596-B1 | 2-(ALPHA-PHENOXY-ALKYL)-IMIDAZOLINES AND THEIR SALTS, THEIR PREPARATION AND USE, AND AGENTS AGAINST PHYTOPARASITIC AND ZOOPARASITIC MITES CONTAINING THEM | CIBA-GEIGY AG (CH) | 1981-12-30 | — | — | EP | disclosed |
| US-4276302-A | PARASITICIDES | CIBA-GEIGY CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |
| EP-0011596-A1 | 2-(Alpha-phenoxy-alkyl)-imidazolines and their salts, their preparation and use, and agents against phytoparasitic and zooparasitic mites containing them | CIBA-GEIGY AG (CH) | 1980-05-28 | — | — | EP | disclosed |
| EP-0011596-A1 | 2-(Alpha-phenoxy-alkyl)-imidazolines and their salts, their preparation and use, and agents against phytoparasitic and zooparasitic mites containing them | CIBA-GEIGY AG (CH) | 1980-05-28 | — | — | EP | disclosed |