Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 14/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 14/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 14/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352087 | 0.90 | NISCH (0.52) | NISCHADRA2AADRA2BADRA2CMAOA | |
| Hydrochloric Acid SCHEMBL11346455 | 0.89 | NISCH (0.51) | NISCHADRA2AADRA2BADRA2CMAOA | |
| SCHEMBL11224297 | 0.87 | NISCH (0.54) | NISCHADRA2AADRA2BADRA2CMAOA | |
| Hydrochloric Acid SCHEMBL9654753 | 0.86 | NISCH (0.53) | NISCHADRA2AADRA2BADRA2CMAOA | |
| SCHEMBL545847 | 0.83 | NISCH (0.50) | NISCHADRA2AADRA2BADRA2CMAOA | |
| SCHEMBL545845 | 0.83 | NISCH (0.50) | NISCHADRA2AADRA2BADRA2CMAOA | |
| Hydrochloric Acid SCHEMBL9654915 | 0.79 | NISCH (0.77) | NISCHADRA2AADRA2BADRA2CMAOA | |
| SCHEMBL3961636 | 0.78 | NISCH (0.50) | NISCHADRA2AADRA2BADRA2CMAOA | |
| SCHEMBL11377087 | 0.78 | ADRA2A (0.52) | NISCHADRA2AADRA2BADRA2CMAOA | |
| SCHEMBL10979198 | 0.77 | NISCH (0.43) | NISCHADRA2AADRA2BADRA2CMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110593-B2 | Phenoxymethyl imidazoline derivatives and their use as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100120881-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-13 | — | — | US | disclosed |
| EP-2117310-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008098657-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-08-21 | — | — | WO | disclosed |
| EP-1958507-A1 | Chemical compounds | Syngeta Participations AG (CH) | 2008-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120881-A1 | CHEMICAL COMPOUNDS | AADAC, ACHE, ATL3 | NISCH 4/4885ADRA2A 1649/4885ADRA2B 2101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.