Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 13/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 13/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 13/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375241 | 0.90 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CHTR1ASLC6A4 | |
| SCHEMBL3961636 | 0.89 | NISCH (0.50) | ADRA2AADRA2BADRA2CHTR1ASLC6A4 | |
| SCHEMBL11377087 | 0.89 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CHTR1ASLC6A4 | |
| SCHEMBL10180172 | 0.86 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CHTR1ASLC6A4 | |
| SCHEMBL11352087 | 0.81 | NISCH (0.52) | ADRA2AADRA2BADRA2CHTR1ANISCH | |
| Hydrochloric Acid SCHEMBL11346455 | 0.81 | NISCH (0.51) | ADRA2AADRA2BADRA2CHTR1ANISCH | |
| SCHEMBL3961615 | 0.79 | NISCH (0.52) | ADRA2AADRA2BADRA2CHTR1ASLC6A4 | |
| SCHEMBL11370259 | 0.79 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CHTR1ASLC6A4 | |
| SCHEMBL3661926 | 0.78 | ADRA2B (0.47) | ADRA2AADRA2BADRA2CHTR1ASLC6A4 | |
| SCHEMBL3667267 | 0.76 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CHTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276302-A | PARASITICIDES | CIBA-GEIGY CORPORATION (US) | 1981-06-30 | — | — | US | claimed |