Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11151604 | 0.84 | TDP1 (0.47) | TSHREPHX1EPHX2TDP1 | |
| SCHEMBL11153682 | 0.81 | KDM4E (0.42) | SIGMAR1L3MBTL1TSHREPHX2KMT2A | |
| SCHEMBL11151594 | 0.79 | TSHR (0.40) | SIGMAR1L3MBTL1TSHRKMT2A | |
| SCHEMBL11155528 | 0.75 | CASP6 (0.38) | TSHRKMT2A | |
| SCHEMBL11149677 | 0.73 | TSHR (0.56) | TSHREPHX1TDP1KMT2A | |
| SCHEMBL11149932 | 0.72 | TSHR (0.44) | L3MBTL1TSHREPHX1KMT2A | |
| SCHEMBL974058 | 0.71 | SIGMAR1 (1.00) | SIGMAR1EPHX1EPHX2 | |
| SCHEMBL6324945 | 0.67 | SIGMAR1 (0.58) | SIGMAR1EPHX1CCR2EPHX2 | |
| SCHEMBL9825772 | 0.66 | SIGMAR1 (0.57) | SIGMAR1EPHX1EPHX2 | |
| SCHEMBL10103544 | 0.66 | SIGMAR1 (0.57) | SIGMAR1EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252795-A | N-substituted dimeric cyclopeptide derivatives and preparation thereof | AYERST MCKENNA AND HARRISON INC. (CA) | 1981-02-24 | — | — | US | disclosed |