Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418170 | 0.85 | L3MBTL1 (0.69) | POLBL3MBTL1NAMPTSMN1; SMN2MAPT | |
| SCHEMBL11354403 | 0.84 | POLB (0.61) | POLBL3MBTL1NAMPTSMN1; SMN2KDM4E | |
| SCHEMBL11353914 | 0.83 | SMN1; SMN2 (0.73) | POLBL3MBTL1NAMPTSMN1; SMN2MAPT | |
| SCHEMBL11355371 | 0.83 | POLB (0.59) | POLBL3MBTL1NAMPTSMN1; SMN2MAPT | |
| SCHEMBL7435574 | 0.83 | POLB (0.59) | POLBL3MBTL1NAMPTSMN1; SMN2MAPT | |
| SCHEMBL2090923 | 0.80 | L3MBTL1 (0.78) | L3MBTL1NAMPTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL11360125 | 0.80 | ALDH1A1 (0.54) | POLBSMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL160520 | 0.78 | POLB (0.68) | POLBL3MBTL1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8307799 | 0.75 | KMT2A (0.59) | POLBSMN1; SMN2HPGDLMNAMEN1 | |
| SCHEMBL11363142 | 0.75 | L3MBTL1 (0.74) | POLBL3MBTL1NAMPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252804-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS | METABIO-JOULLIE (FR) | 1981-02-24 | — | — | US | disclosed |
| US-4252804-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS | METABIO-JOULLIE (FR) | 1981-02-24 | — | — | US | disclosed |