Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18257816 | 0.88 | KMT2A (0.73) | KMT2ASMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL20327274 | 0.87 | KMT2A (0.76) | KMT2ASMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL7433455 | 0.85 | KMT2A (0.59) | KMT2ASMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL160520 | 0.79 | POLB (0.68) | SMN1; SMN2LMNAHTTKDM4EPOLB | |
| SCHEMBL23244269 | 0.78 | GFER (0.64) | KMT2AHTTKDM4EHSD17B10MEN1 | |
| SCHEMBL1617351 | 0.77 | KMT2A (0.56) | KMT2ASMN1; SMN2LMNAKDM4EHSD17B10 | |
| SCHEMBL11355367 | 0.75 | POLB (0.59) | KMT2ASMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL8308417 | 0.75 | KDM4E (0.67) | KMT2ASMN1; SMN2LMNAKDM4EHSD17B10 | |
| SCHEMBL7046945 | 0.73 | PTGS2 (0.57) | KMT2ASMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL3768296 | 0.73 | KMT2A (0.49) | KMT2AKDM4EHSD17B10MEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |